{"id":428,"date":"2019-02-17T23:27:49","date_gmt":"2019-02-17T22:27:49","guid":{"rendered":"https:\/\/bogenommedicinskcannabis.dk\/?page_id=428"},"modified":"2019-02-23T13:38:30","modified_gmt":"2019-02-23T12:38:30","slug":"et-klinisk-forsoeg-med-cannabis-mod-hjernekraeft","status":"publish","type":"page","link":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/artikler\/medicinsk-cannabis-og-kraeft\/et-klinisk-forsoeg-med-cannabis-mod-hjernekraeft\/","title":{"rendered":"Et klinisk fors\u00f8g med cannabis mod hjernekr\u00e6ft"},"content":{"rendered":"

Tidlige studier med b\u00e5de gnavere og humane cellekulturer har vist, at stoffer i cannabis standser v\u00e6kst, spredning og migration af glioma celler.[1]<\/a> Glioma er en sj\u00e6lden og aggressiv form for kr\u00e6ft, som starter i hjernen og rygs\u00f8jlen. Sm\u00e5 humane studier har vist overraskende gode tegn p\u00e5 succes med cannabis behandling. I et fase-2 fors\u00f8g med 21 behandlings-resistente glioblastoma patienter, behandlede forskerne patienterne med et l\u00e6gemiddel, som indeholdt isolerede cannabis ekstrakter.[2]<\/a><\/p>\n

Dette l\u00e6gemiddel indeholdt b\u00e5de THC[3]<\/a> og CBD.[4]<\/a> Patienterne fik ogs\u00e5 temozolomide, som er et kemopr\u00e6parat. I dette fors\u00f8g overlevede 83% af patienterne 1 \u00e5r. 1 \u00e5rs overlevelsen var kun 53% for placebo-gruppen.<\/p>\n

\"\"<\/p>\n

Professor Susan Short, den ledende forsker p\u00e5 studiet:
\n<\/strong>\u201dFundene fra dette vel-designede, kontrollerede studie viser, at tilf\u00f8jelsen af en kombination af THC og CBD til patienter til dosis-intensiv temozolomide gav relevante forbedringer i overlevelsen sammenlignet med placebo og dette er et godt signal for en potentiel effekt. Derudover blev cannabis medicinen generelt godt tolereret. Disse lovende resultater er af s\u00e6rlig interesse, da THC:CBD produktets farmakologi synes at v\u00e6re forskellig fra de eksisterende kr\u00e6ftmidler og kan give en unik og sandsynlivis synergistisk mulighed for fremtidig behandling af glioma.\u201d[5]<\/a><\/p>\n

 <\/p>\n

[1]<\/a> Mar\u00eda Salazar<\/a>,1,2<\/sup> Arkaitz Carracedo<\/a>,1<\/sup> \u00cd\u00f1igo J. Salanueva<\/a> et al.: Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest<\/a>. 2009 May 1; 119(5): 1359\u20131372.
\nPublished online 2009 Apr 1. doi:\u00a0 10.1172\/JCI37948<\/a> https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2673842\/<\/a>
\nhttp:\/\/herb.co\/2017\/07\/20\/cannabis-cancer-treatment\/<\/a>
\n[2]<\/a> GW Pharmaceuticals Achieves Positive Results in Phase 2 Proof of Concept Study in Glioma. https:\/\/www.gwpharm.com\/about-us\/news\/gw-pharmaceuticals-achieves-positive-results-phase-2-proof-concept-study-glioma<\/a>
\n[3]<\/a> THC: Everything You Need To Know About Delta9-Tetrahydrocannabinol. http:\/\/herb.co\/2016\/07\/24\/what-is-thc\/<\/a>
\n[4]<\/a> CBD: Everything You Need To Know About Cannabidiol. http:\/\/herb.co\/2016\/07\/26\/everything-you-need-to-know-about-cbd\/<\/a>
\n[5]<\/a> GW Pharmaceuticals Achieves Positive Results in Phase 2 Proof of Concept Study in Glioma. https:\/\/www.gwpharm.com\/about-us\/news\/gw-pharmaceuticals-achieves-positive-results-phase-2-proof-concept-study-glioma<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Tidlige studier med b\u00e5de gnavere og humane cellekulturer har vist, at stoffer i cannabis standser v\u00e6kst, spredning og migration af glioma celler.[1] Glioma er en sj\u00e6lden og aggressiv form for kr\u00e6ft, som starter i hjernen og rygs\u00f8jlen. Sm\u00e5 humane studier … L\u00e6s resten →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":306,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-428","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/pages\/428","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/comments?post=428"}],"version-history":[{"count":3,"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/pages\/428\/revisions"}],"predecessor-version":[{"id":547,"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/pages\/428\/revisions\/547"}],"up":[{"embeddable":true,"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/pages\/306"}],"wp:attachment":[{"href":"https:\/\/bogenommedicinskcannabis.dk\/index.php\/wp-json\/wp\/v2\/media?parent=428"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}